Determination of spatial mercury concentration by laser ablation-inductively coupled plasma mass spectrometry

Laser ablation-inductively coupled plasma mass spectrometry (LA-ICP-MS) is capable of metal imaging by acquiring local spatial information. However, the preparation an appropriate standard for quantitative analysis difficult because matrices between and sample should match, homogeneity concentration in required. Hence, aim this study was to establish a highly mercury method that utilizes LA-ICP-MS consisting rat tissue. Our showed homogeneous good linearity signal intensity, met qualifications LA-ICP-MS. Mercury MeHg-exposed kidneys obtained measurement (7.84 ± 0.57 µg/g) comparable cold vapor atomic absorption spectrophotometry (AAS, 7.27 0.46 µg/g). The results indicate enabled with standard.